Professor Françoise Denoyelle is currently Otolaryngologist, Head and Neck Surgeon in the Pediatric Otolaryngology-Head and Neck Surgery Department, Necker-Enfants Malades Children’s Hospital, Paris, France; Professor of University Paris V; and team leader of the INSERM U587 team “Phenotype-genotype relationships of genetic hearing impairment and hearing rehabilitation”
Professional societies include:
- Vice-president of the French College of Teachers of Otolaryngology (Head and and Neck Surgery) since 2012
- Member of the Scientific Committee of ESPO (European Society of Ped. Otolaryngology)
- Member of the Board of Directors of SIFORL since 2003
- President of the ACFOS Association (Action Connaissance Formation pour la Surdité)
- Past-President of the French Association of Pediatric Otolaryngologists (AFOP) 2007-2009
- Past-President of the committee « Evaluation et Expertise » and member of the board of the Société Française d’ORL et de Pathologie Cervicofaciale
Her major interests are:
- Surgery: pediatric otology, external ear and middle ear reconstruction, pediatric laryngology. Leader of the French Referral Centre for rare otolaryngologic malformations
- Research: Genetics of hearing impairment. Hearing implants
Main publications include:
– Célérier C, Thierry B, Coudert C, Blanchard M, Loundon N, Garabédian EN, Denoyelle F. Results of VSB implantation at the short process of the incus in children with ear atresia. Int J Pediatr Otorhinolaryngol. 2017 Feb;93:83-87.
– Simon F, Celerier C, Garabedian EN, Denoyelle F. Mastoid fascia kite flap for cryptotia correction. Int J Pediatr Otorhinolaryngol. 2016 Nov;90:210-213.
– Denoyelle F, Coudert C, Thierry B, Parodi M, Mazzaschi O, Vicaut E, Tessier N, Loundon N, Garabedian EN. Hearing rehabilitation with the closed skin bone-anchored implant Sophono Alpha1: results of a prospective study in 15 children with ear atresia. Int J Pediatr Otorhinolaryngol. 2015 Mar;79(3):382-7.
– Harterink E, Leboulanger N, Kotti S, Garabedian EN, Denoyelle F. Results of myringoplasty in children with cleft palate: a patient-matched study. Otol Neurotol. 2014 Jun;35(5):838-43. 15.
– Philippon D, Laflamme N, Leboulanger N, Loundon N, Rouillon I, Garabedian EN, Denoyelle F. Hearing outcomes in functional surgery for middle ear malformations. Otol Neurotol. 2013 Oct;34(8):1417-20.
– Denoyelle F, Leboulanger N, Coudert C, Mazzaschi O, Loundon N, Vicaut E, Tessier N, Garabedian EN. New closed skin bone-anchored implant: preliminary results in 6 children with ear atresia. Otol Neurotol. 2013 Feb;34(2):275-81.
– Bonnet C, Grati M, Marlin S, Levilliers J, Hardelin JP, Parodi M, ….et Denoyelle F. Complete exon sequencing of all known Usher syndrome genes greatly improves molecular diagnosis. Orphanet J Rare Dis 2011;6:21.
– Denoyelle F, Garabédian EN. Propranolol may become first-line treatment in obstructive subglottic infantile hemangiomas. Otolaryngol Head Neck Surg 2010;142:463-4.
– Marlin S, Feldmann D, Nguyen Y, Rouillon I, Loundon N, … et Denoyelle F. Temperature-sensitive auditory neuropathy associated with an otoferlin mutation: Deafening fever! Biochem Biophys Res Commun 2010;394:737-42.
– Albert S, Blons H, Feldmann D, Loundon N, …et Denoyelle F. SLC26A4 gene is frequently involved in nonsyndromic hearing impairment with enlarged vestibular aqueduct in Caucasian populations. Eur J Hum Genet 2006;14:773-9.
– Denoyelle F, Lina-Granade G, Plauchu H, Bruzzone R, Chaib H, Levi-Acobas F, Weil D, Petit C. Connexin 26 gene linked to a dominant deafness. Nature 1998;393:319-20.
– Denoyelle F, Weil D, Maw MA, Wilcox SA, Lench NJ, … et Petit C. Prelingual deafness: high prevalence of a 30delG mutation in the connexin 26 gene. Hum Mol Genet 1997;6:2173-7.