Dr Subramania Iyer had higher surgical training in head and neck surgery and plastic surgery from the All India Institute of Medical Sciences New Delhi, Medical College Calicut and various centers in the United Kingdom. He did fellowship training in craniofacial surgery in Mexico City with Dr Ortiz Monasterio, in laryngeal cancer surgery in Center Oscar Lambrette, Lille with Prof Lefebvre, Tissue engineering in Rice University, Houston with Prof Antonios Mikos. He also underwent training in robotic surgery in Korea and endoscopic thyroid surgery in Vietnam.
He initiated the plastic surgery and head and neck surgery departments at the at Amrita Institute of Medical Sciences, Kochi holding currently the position of Professor and Chairman Plastic/Reconstructive Surgery / Head and Neck Surgery/ Craniomaxillofacial Surgery. He is a PhD guide in Amrita University. He took the lead in organizing structured training programme for head and neck surgical oncology in the country. He has trained over 400 surgeons in microvascular head and neck reconstruction so far.
He officiated as the President of the Indian Society of Facial Plastic Surgery the FHNO (Indian Head and Neck Society) and Association of Plastic Surgeons of India. He is the past Secretary of the Indian Society of Microsurgery and the FHNO
He led the team that carried out the first two double hand transplants / double forearm / upper arm transplants in south Asia. The team also did the first tracheal allotransplant in India. His team won the best surgical team of south Asia in 2015 awarded by the BMJ.